Friday, October 20, 2006

Photodynamic Therapy for Skin Cancer

There will be nearly 11,000 deaths from skin cancer in 2006 — about 8,000 from melanoma and 3,000 from other skin cancers, says the American Cancer Society.
Skin cancer is the most common of all cancers and accounts for almost half of all cancers in the United States. There are two types of skin cancer, nonmelanoma and melanoma.
U.S. doctors find more than 1 million cases of nonmelanoma skin cancer, usually in a patient´s basal cells or squamous cells. Exposing skin — the face, ear, neck, lips, and the backs of the hands — to the sun causes most nonmelanoma skin cancer. While they can grow fast or slow, they rarely spread to other parts of the body.
The second kind, melanoma does spread to other areas of the body making it more dangerous. It accounts for just a small percentage of skin cancer, but it causes most skin cancer deaths. Melanoma is a cancer that begins in the pigment cells that produce the skin coloring (melanin) which helps protect deeper layers of the skin from the sun´s harmful rays. Detected early, melanoma is almost always curable.
Photodynamic therapy
Both nonmelanoma and melanoma skin cancers respond to photodynamic therapy (PDT). PDT is a Food and Drug Administration (FDA) approved treatment for skin cancer that combines a light source and a photosensitizing agent (a drug that is activated by light) to destroy cancer cells. It´s sometimes called photoradiation therapy, phototherapy or photochemotherapy and is useful when there are several lesions on the skin or scalp.

A photosensitizing agent, for example fluorouracil, spread on the skin makes PDT work, because the agent collects more readily in cancer cells than in normal cells. Exposing the agent to light makes it react with oxygen to create chemicals that can kill a skin cancer cell. However, the approved light sources can only penetrate a limited depth of tissue; therefore doctors mainly use PDT to treat areas on or just under the skin. It´s less effective for treating large tumors, because the light cannot pass deep into the tumors. Because it´s a localized treatment, doctors don´t use PDT to treat skin cancer that has metastasized.
Doctors sometimes use PDT in precancerous treatments. It usually needs pre-approval by a healthcare provider. Just because the treatment is in the facial area, case managers shouldn´t assume it´s a cosmetic treatment. Check to see the patient´s age, if the patient is over 60 years old, the case is probably not cosmetic. Also, look at the chart to see if there are multiple lesions on the skin or scalp, usually three or more.
About AllMed Healthcare Management
Founded in 1995, AllMed is a URAC-accredited Independent Review Organization (IRO) serving insurance payers, providers, TPAs and claims managers nationwide. Reviews are conducted by board-certified physicians in active practice. AllMed's growing customer base for its independent medical review and hospital peer review services includes premier organizations, such as Educator's Mutual Life, IMS Managed Care, Tenet Healthcare Corporation, HealthGuard, several Blue Cross Blue Shield organizations, TriWest Healthcare Alliance, Allianz and many other leading healthcare payers. Read the AllMed Medical News Blog and the Independent Review Organization Blog.

Sunday, October 15, 2006

Skin Cancer - A Reminder

We need to get alerted: skin cancer is the most popular cancer. Every year, more than 1,000,000 skin cancer cases are diagnosed and tens of thousands of skin cancer patients die in the U.S. alone. The number of skin cancer exceeds that of all other cancers combined. Among more than 1 million of skin cancer cases, 100,000 are melanoma, the deadliest skin cancer and there is no cure for it.
The skin cancer risk is more serious to the children because they are young and more susceptible, and they expose to more sunlight than adults due to their extensive outdoor activities. Half of the total life time exposure for an individual is received during his childhood. So special care is needed for the children.
Usually, skin cancers come years later after the subjects get exposed to too much sunlight. So just because you do not see a skin cancer right away does not mean you are free of skin cancer risk. So careful protection is the key.

Tuesday, October 10, 2006

Sun Exposure & UV Rays: The Basic Facts

The human body benefits from sun exposure. And a little bit of tan protects you from the sun. Right? Wrong!
The body does indeed benefit from sun exposure. But a little bit of tan does not necessarily protect you from the sun. Let’s see why.
The sun’s rays are a major source of vitamin D and help the body’s systems acquire much needed calcium for building healthy bones. However, most people don’t need to spend large amounts of time exposed to the sun in order to get their required amount of vitamin D.
In fact, the body’s health can actually suffer negative effects when it’s exposed too long to the sun’s rays, especially if it’s unprotected. Results can vary from skin and eye damage to immune system suppression and ultimately cancer, even for the young.
So let’s look at the basic facts about sun exposure.
There are three kinds of invisible ultraviolet (UV) rays in the sun that reaches earth: UVA, UVB, and UVC. When these rays come in contact with our skin, affects of UVA and UVB can be - tans, burns and other reactions (e.g. like acne and cancer).
It’s also notable that the effects of all UV rays are not the same. Depending upon the season, time of day and place on the planet in relation to the sun - (i.e. your altitude and latitude), the rays’ intensities vary. For example, during summertime, UV rays are at their strongest. Between 10 a.m. and 4 p.m., the rays are strongest. And close to the equator and at high altitudes (where air and cloud cover are less, resulting in increased harmful penetration of UV rays into the environment), the rays are also strongest.
In order to protect ourselves from the harmful UV rays, let’s look at the skin’s first defense - melanin.

Melanin is a chemical present in a variety of colors and concentrations in most people's skin that helps with defense from the sun. Melanin reacts with UV rays and absorbs them. Or rather, to be more specific, the rays act upon melanin, causing the melanin to spread out or grow, increasing its presence in response to the sun’s exposure. The result? A ‘sun tan’. The darker the skin color, the more melanin the skin has for protection. And ‘tanning’ for darker color is included here; ‘color’ does not have to refer to just the original skin color.
A word of caution…
Tanning may look great on the surface, - but the amount and length of time a person is exposed to the sun, determines the amount of possible damage. It also determines the future risk of damage that’s likely.
For example, people who are exposed to the sun in huge doses like ship crews, field workers and beach surfers, are at higher risks for skin damage than indoor workers. What happens is that when the amount of UV exposure is greater than what the skin's melanin can handle, sunburn can result. And those with lighter, fairer skin, who have less melanin, absorb less UV, suffering less protection.
Since research has shown that UV damage from the sun is the main cause of skin cancer, (with as high as 20% of some populations developing skin cancer during their lifetime), we need to take a proactive approach in relation to sun exposure to avoid harmful skin damage.
As we say colloquially here in Australia - “Slip, Slop, Slap”. (I.e. ‘Slip’ on a shirt, ‘Slop’ on a hat, ‘Slap’ on a sunscreen). Look after the skin you’ve got, because you’re the one who will be living with it!
Angela Perin is author of the comprehensive new guide "Your Personal Guide to Tanning" - covering everything from your skin, uv light & sun-tanning, to sunburn, skin cancer, sunburn, sun protection and sunless tanning. Discover Safe Tan - The Ultimate Experience in Natural Sunless Tanning and download your free copy of this guide including bonus homemade recipes for sunburn relief, sunscreen and exfoliation!